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. 2022 Apr 7;13(4):313. doi: 10.1038/s41419-022-04753-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A SorCS3 expression level in adjacent normal tissues (n = 5), low grade glioma tissues (n = 511) and GBM (n = 154) in the glioma datasets from TCGA. B Kaplan-Meier Survival curves of different SorCS3 expression levels for GBM in TCGA dataset (High SorCS3, n = 338; Low SorCS3, n = 338; p < 0.001). C, D SorCS3 expression with different WHO grade glioma and normal brain tissues taken from 108 patients was assessed by IHC. Scale bar: 100 µm. *p < 0.05; **p < 0.01; ***p < 0.001, ns: not statistically significant.