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. 2022 Apr 7;13(4):314. doi: 10.1038/s41419-022-04736-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A The cell proliferation inhibition rate was detected by CCK-8 assay. B The effect of lncRNA-Gm31932 on morphological changes in B16 cells. C Representative images of cell colonies. D The colony formation inhibition rate. E Changes in the melanin content of B16 cells. F Changes in the tyrosinase activity in B16 cells. G The effect of lncRNA-Gm31932 on the B16 cell cycle was detected by flow cytometry. H Quantitative analysis of cell cycle distribution. n = 3. Data are presented as the mean ± SD. *P < 0.05, **P < 0.01 compared with the corresponding control group by Student’s t-test.