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. 2022 Mar 25;16:838942. doi: 10.3389/fnins.2022.838942

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Copyright © 2022 Zhou, Zheng, Chen, Yan, Peng, Liu, Zhang, Tang and Wen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The series of diagrams illustrates the patterns of dynamic changes of gene in each group. Clusters 1 and 8 presented a trend of increasing in the VPA-induced autism model group and decreasing in the AVP group. Clusters 5 and 7 presented a trend of decreasing in the VPA-induced autism model group and increasing in the AVP group. Clusters 2 and 6 presented a trend of gradually declining in the VPA-induced autism model group and AVP group, and clusters 3 and 4 presented a trend of continuous increase in the VPA-induced autism model group and AVP group.