Table 1.
Patient's biochemical, hematological, and immunological data from birth until 3 months old.
| Range | 14 days old | 1 month old | 2 months old | 4 months old | |
|---|---|---|---|---|---|
| RBC | 3.1–4.5 × 106/μl | 3.71 | 3.93 | 3.75 | 4.16 |
| HGB | 10–14 g/dl | 11.3 | 11.2 | 9.9 | 10.9 |
| HCT | 27%−42% | 33.3 | 33.1 | 31.9 | 33.1 |
| MCV | 75–95 fl | 89.8 | 84.2 | 85.1 | 79.6 |
| MCH | 26–35 pg | 30.5 | 28.4 | 28.8 | 26.2 |
| MCHC | 28–36 g/dl | 33.9 | 33.7 | 33 | 32.9 |
| RDW | 11.6%−16.5% | 15.9 | 16.9 | 16.2 | 15.4 |
| PLT | 150,000–350,000/μl | Not available | 135,000 | 213,000 | 533,000 |
| MPV | 7.1–10 fl | Not available | 9.3 | 8.5 | 8.4 |
| WBC | 5,000–15,000 cell/μl | 5,400 | 4,300 | 7,000 | 12,600 |
| % Neutrophils | 10%−50% | 37.6 | 23 | 27.5 | 37.2 |
| % Lymphocytes | 40%−80% | 49.3 | 67.7 | 56.1 | 43.3 |
| CD3 | 2,500–5,500 cell/μl | 3,279 | 4,016 | 4,944.9 | |
| % CD3 | 55%−80% | 96 | 91 | 90.9 | |
| HLADR+ | % | 2.9 | |||
| CD4 | 1,600–4,000 cell/μl | 2,879 | 3,073 | 3,884.1 | |
| %CD4 | 30%−50% | 84 | 70 | 71.4 | |
| CD3+CD8+ | 190–1,140 cell/μl | 343 | 874 | ||
| %CD3+CD8+ | 14%−38% | 10 | 20 | ||
| CD45RO | % | 16 | |||
| CD45RA+31+ | % | 69 | |||
| CD45RA+31+ | % | 82 | |||
| CD4/CD8 | 1.4–2.7 | 8.4 | 3.5 | 3.9 | |
| CD19 | 90–660 cell/μl | 3 | 24 | 8 | |
| % CD19 | 6%−25% | 0.1 | 0.5 | 0.14 | |
| CD56CD16+ | 5%−24% | 110 | 329 | 446 | |
| % CD56CD16 | 8%−17% | 3 | 8 | 8.2 | |
| IgG | 232–1411 mg/dl | 564 | 526 | 277 | 326 (after IRT) |
| IgM | 5–145 mg/dl | 0 | 1 | 7 | 5 |
| IgA | 5–83 mg/dl | 1 | <5 | <5 | <5 |
| TREC on dried blood spot | Normally expressed | Normally expressed | |||
| KREC on dried blood spot | No expression | No expression | No expression | ||
| C26 | 0.2–0.9 μmol/L | 8 | |||
| C24/C22 | 0.6–1.2 μmol/L | 1.5 | |||
| C26/C22 | 0–0.030 μmol/L | 0.24 | |||
| AST | 8–60 UI/L | 783 | 424 | 473 | |
| ALT | 7–45 UI/L | 469 | 162 | 190 | |
| Total bilirubin | 0–1.2 mg/dl | 0.24 | 0.28 | ||
| Direct bilirubin | 0–0.3 mg/dl | 0.2 | 0.23 | ||
| Gamma-GT | 8–127 UI/L | 222 | 143 | 130 |
IRT, immunoglobulin replacement therapy; RBC, red blood cells; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red cell distribution width; PLT, platelet; MPV, mean platelet volume; WBC, white blood cell; TREC, T-cell receptor excision circle; KREC, κ-deleting recombination excision circle; AST, aspartate transaminase; ALT, alanine transaminase.