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. 2022 Mar 24;9(1):e28639. doi: 10.2196/28639

Table 2.

Technological characteristics and human factors influencing and shaping the relationship and collaboration between AI-enabled clinical decision support systems (CDSSs) and human actors.

Parameters Definition Study
Technological characteristics

Training data quality Information used for training of AI-enabled CDSSs to create a truthful, reliable, and representative system [53]

Performance The accuracy and reliability of an AI-enabled CDSS [30,55]

Explainability or transparency An AI-enabled CDSS' ability to ensure that a human actor understands the processes that lead to the prediction and the prediction itself [30,31,54-56]

Adapted output or adaptability The degree to which an AI-enabled CDSS fits into a specific context or environment according to the subdimensions simplicity, granularity, and concreteness [31]
Human factors


Medical expertise The degree of medical experience of a human actor within the context of collaboration with an AI-enabled CDSS [30,31,54,57]

Technological expertise The degree of technological experience of a human actor with regard to an AI-enabled CDSS [30,54]

Personality A medical professional’s attributes and characteristics that influence the interaction with AI-enabled a CDSS [54]

Cognitive biases The cognitive processes that alter rational decision-making and perceptions of an AI-enabled CDSS [30,54]

Trust The subjective impression of a medical professional that an AI-enabled CDSS is truthful and reliable [30,53,54]