TABLE 8.
Inhibition of cell proliferation by QYL-438, QYL-769, and GCV in various cells
| Test type | IC50 (μM) of:
|
||
|---|---|---|---|
| QYL-438 | QYL-769 | GCV | |
| Cell proliferation, Daudi | 12.9 | 27.9 | 196 |
| Cell proliferation, HFFa | 278 | 255 | 157 |
| Bone marrow (CFU-GM) (4)b | 55.7 | 77.5 | 35.3 ± 9.7 |
| Bone marrow (BFU-E) (4) | 162 | 130 | 6.6 ± 1.0 |
Data from Table 7.
Number of experiments shown in parentheses. Results for GCV are given as means ± standard deviations.