Table 5.
Cox proportional-hazard regression analysis for DFS in HCC patients
| Variables | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| HR (95%CI) | P-value | HR (95%CI) | P-value | |
| COMMD3 (high vs. low) | 2.011 (1.490-2.714) | ≤0.001 | 1.782 (1.344-2.426) | ≤0.001 |
| Age (≥60 vs. <60 years) | 1.035 (0.772-1.388) | 0.818 | ||
| Sex (man vs. female) | 1.178 (0.864-1.607) | 0.301 | ||
| Race (white vs. others) | 1.314 (0.993-1.740) | 0.056 | ||
| G stage (G3+G4 vs. G1+G2) | 1.022 (0.764-1.366) | 0.886 | ||
| TNM stage (III+ IV vs. I+ II) | 1.726 (1.275-2.336) | ≤0.001 | 1.004 (0.660-1.444) | 0.982 |
| T stage (T3+T4 vs. T1+T2) | 2.240 (1.633-3.072) | ≤0.001 | 2.023 (1.271-3.218) | 0.003 |
| Vascular invasion (Yes vs. No) | 2.009 (1.425-2.833) | ≤0.001 | 1.066 (0.847-1.340) | 0.588 |
DFS, disease free survival; HCC, hepatocellular carcinoma; HR, hazard ratio; CI, confidence interval.