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. 2022 Mar 28;13(6):2029–2039. doi: 10.7150/jca.63533

Figure 4.

Figure 4

Overexpression of NRCAM could rescue the enhanced effect of miR-338-3p on osteosarcoma cells. (A-C) The role of miR-338-3p and NRCAM in the proliferation of osteosarcoma cells was measured across cell viability as well as colony formation. (D) EdU incorporation assays were performed to assess the role of miR-338-3p and NRCAM on cell proliferation ability. Scale bars = 100μm. (E, F) The function of miR-338-3p and NRCAM in the invasion and migration of osteosarcoma cells was analyzed by employing transwell assay. (G) The function of miR-338-3p and NRCAM on osteosarcoma cells mobility were evaluated by wound-healing assay. Scale bars = 100μm. Data was presented as mean ± SD from three independent experiments. *, P <0.05.