The reciprocal interaction of LINC00491 and miR-188-5p in PC cells migration, invasion and proliferation. A-B. CCK-8 assay and colony formation assay were conducted to evaluate the proliferation abilities of SW1990 and MIAPaCa-2 transfected with si-Con, si-LINC00491, miR-188-5p inhibitor, si-LINC00491 and miR-188-5p inhibitor, respectively. C-D. Transwell assays indicated the ability of migration and invasion in SW1990 and MIAPaCa-2 under the corresponding treatment. *p<0.05, **p<0.01, ***p<0.001. Each experiment was repeated in 3 independent trials and mean ± SD was used to descripted the results.