Figure 3.
Effect of CCT3 knockdown on the proliferation of melanoma cells. (A) The infected cells expressing GFP imaged and counted using the Cellomics ArrayScan High Content Screening (HCS) Reader once a day for five days. The cell growth curves in shCtrl- and shCCT3-infected A375 and MUM-2C cells are shown. (B) The cell proliferation of A375 and MUM-2C cells with and without CCT3 knockdown evaluated by MTT assay. (C) Colony formation evaluated in A375 and MUM-2C cells with and without CCT3 knockdown. Data are expressed as mean ± SD (n=3), shCtrl vs. shCCT3, *P < 0.05, ** P < 0.01, *** P < 0.001.
