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. 2022 Mar 28;13(6):1958–1971. doi: 10.7150/jca.69497

Figure 5.

Figure 5

CCT3 expression knockdown attenuated the tumorigenicity of A375 cells in vivo. (A) Nude mice subcutaneously inoculated with A375-LV-shCCT3 and control cells to test their proliferative ability in vivo. Tumor images resected from mice in shCCT3 and shCtrl group. Average volume (B) and weight (C) of the subcutaneous xenografts in shCtrl and shCCT3 groups. (D) Immunohistochemistry results showing the expression of CCT3 in paraffin-embedded xenograft tissues (original magnification, 200×; Scale bar: 50 μm). Data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, compared with shCtrl group.