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Apoptosis of cancer associated fibroblasts (CSF) in LLC mice treated with CNP-302. LLC tumor-bearing mice were treated with ONP-302 (50mg/kg) intravenously twice per week for 2 weeks and tumor tissues were prepared for the staining. A. Typical example of tumor tissue staining with αSMA. Scale = 50 μm. B. Typical example of Masson's trichrome staining = 50 μm.
