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TDG inhibited the migration, invasion and metastasis of colon cancer cells. (A-B) The overexpression efficiency of TDG was detected by qRT-PCR and western blotting. (C) The transwell assay was performed for migration and invasion of colon cancer cells. (D-E) Migration and invasion related molecules were detected by qRT-PCR and western blotting. F. Construction of metastatic tumor model in nude mice. *P<0.05, **P<0.01, ***P<0.001.
