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. 2022 Mar 21;18(6):2540–2552. doi: 10.7150/ijbs.70708

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p-LYN level is elevated in CRC and positively correlates with CRC metastasis. (A) Immunohistochemical staining was performed to examine the expression of p-LYN in the patient's CRC tissues and adjacent tissues. (B) The score of p-LYN staining in (A). (C) Immunohistochemical determination of p-LYN expression in each pathological stage of CRC. (D) The score of p-LYN staining in (C). (E) Kaplan-Meier analysis of the overall survival of 88 CRC patients based on PSAT1 expression. (F) Representative images of immunohistochemical staining of p-LYN, E-Cadherin, and N-Cadherin in CRC tissues. (G-H) Correlation analysis of the immunostaining intensity of p-LYN with E-Cadherin (G) or N-Cadherin (H). ^** P < 0.01; ^***; P < 0.001; ^****, P < 0.0001.