FIGURE 6.

Exosomal miR‐9‐5p influences fibroblast phenotypic transformation through NOX4/TGF‐β1 signaling. A, B, Protein levels of αSMA were assessed and quantified by western blot analysis. C, Flow cytometry analysis of DCFH‐DA fluorescence in HGF‐1 treated with TGF‐β1 for 48 h after transfection with miR‐9‐5p mimic or mimic NC. D, Flow cytometry analysis of DCFH‐DA fluorescence in HGF‐1 treated with TGF‐β1 for 48 h after transfection with miR‐9‐5p inhibitor or inhibitor NC. E‐G, Protein levels of αSMA and NOX4 were assessed and quantified by western blot analysis in HGF‐1 treated with TGF‐β1 for 48 h after transfection with miR‐9‐5p mimic or mimic NC. H, I, Immunofluorescence analysis of αSMA and NOX4 in HGF‐1 treated with TGF‐β1 for 48 h after transfection with miR‐9‐5p mimic or mimic NC. *P < .05, **P < .01, ****P < .0001