Table 2.
Univariable and multivariable logistic regression analysis of variables potentially associated with GDM during the subsequent pregnancy.
| n/N (%) | Crude OR | 95%CI | p-value | Adjusted OR | 95%CI | p-value | |
|---|---|---|---|---|---|---|---|
| Maternal age ≥ 35 years☨ | 34/307 (11.1) | 1.24 | (0.83-1.85) | 0.301 | 1.12 | (0.70-1.78) | 0.643 |
| Pre-pregnancy BMI ≥ 25.0☨ | 37/139 (26.6) | 4.21 | (2.76-6.41) | <0.001* | 2.65 | (1.61-4.36) | <0.001* |
| GDM☨ | 48/70 (68.6) | 29.54 | (17.19-50.74) | <0.001* | 26.22 | (14.93-46.07) | <0.001* |
| Macrosomia☨ | 5/19 (26.3) | 3.48 | (1.24-9.79) | 0.018* | 2.08 | (0.60-7.22) | 0.249 |
| Pregnancy interval, years | – | 1.13 | (0.96-1.33) | 0.131 | 1.10 | (0.92-1.32) | 0.276 |
| Anuual BMI change, kg/m2/year | – | 1.42 | (1.18-1.71) | <0.001* | 1.48 | (1.22-1.81) | <0.001* |
| High parity (Parity ≥ 2) | 38/365 (10.4) | 1.14 | (0.78-1.68) | 0.507 | 1.18 | (0.77-1.81) | 0.459 |
n/N: The number of GDM events during the subsequent pregnancy/the number of patients for each variables; OR, odds ratio; CI, confidence interval; BMI, body mass index; GDM, gestational diabetes mellitus.
☨Variables during the index pregnancy. *Statistically significant.