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Hypervascularization in the islets of Wolfram syndrome mouse model. (A) Representative immunofluorescent images of islets from Wfs1 wild-type (WT) and whole-body knockout 129S6 (KO) male mice at 10 months of age. Scale bars 50 µm. (B) Quantification of endothelial cell marker (CD31) positive area and islet area composition (WT, n=33; KO, n=34). Data are shown as mean ± SEM, ****P < 0.001.
