| Methods |
DURATION OF INTERVENTION:
2 years
DURATION OF FOLLOW‐UP:
2 years
LANGUAGE OF PUBLICATION:
English |
| Participants |
WHO PARTICIPATED:
Chinese girls, aged 10 years at inclusion
INCLUSION CRITERIA:
free of any disease that might affect bone development
EXCLUSION CRITERIA:
see above
DIAGNOSTIC CRITERIA:
clinical assessment
CO‐MORBIDITIES:
not stated
CO‐MEDICATIONS:
not stated |
| Interventions |
NUMBER OF STUDY CENTRES:
1
COUNTRY/ LOCATION:
China, urban
SETTING:
cluster study with primary schools as cluster
INTERVENTION (ROUTE, TOTAL DOSE/DAY, FREQUENCY):
I1: fortified milk with calcium 560 mg/school day, averaged 245 mg/day
I2: fortified milk with calcium 560 mg plus vitamin D3 200 (during first third of study) or 320 (during second and third third of study) IU/school day, averaged calcium 245 mg plus vitamin D3 133 IU/day
CONTROL (ROUTE, TOTAL DOSE/DAY, FREQUENCY):
none
TREATMENT BEFORE STUDY:
not stated |
| Outcomes |
PRIMARY OUTCOME(S):
bone mineral content, bone area, bone mineral density, total body composition, 25‐hydroxyvitamin D in blood, intact parathyroid hormone in blood, blood calcium in blood, calcium/creatinine ratio in urine, weight, length, sitting height, clinical signs of rickets
SECONDARY OUTCOMES:
no distinction made between primary and secondary outcomes |
| Notes |
STATED AIM OF STUDY:
to examine the effects of providing a dietary supplement of a small volume of milk to Chinese pre‐pubertal girls in Beijing |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
