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. 2022 Mar 25;9:781888. doi: 10.3389/fmed.2022.781888

TABLE 2.

Factors associated with log-transformed anti-S1-RBD IgG titers in HD Patients.

Variable Univariate
Multivariate
B coefficient 95% CI p-value B coefficient 95% CI p-value
Age (per year) −0.02 −0.03 −0.01 0.004 −0.015 −0.025 −0.004 0.006
Female −0.04 −0.32 0.23 0.768
Dialysis vintage (per month) 0.00 0.00 0.00 0.983
DM 0.00 −0.26 0.26 0.975
IHD −0.08 −0.33 0.18 0.548
Malignancy Hx −0.28 −0.59 0.02 0.066
Transplantation Hx −0.29 −0.95 0.37 0.391
Dialysis access (jugular catheter vs. AVF) −0.06 −0.31 0.20 0.664
KT/V 0.27 −0.20 0.75 0.259
nPCR 0.42 −0.05 0.89 0.077
Residual renal function 0.14 −0.11 0.39 0.277
BMI (per kg/m2) −0.01 −0.04 0.01 0.403
BMI > 30 −0.18 −0.46 0.11 0.222
Hemoglobin (per gr/dL) −0.03 −0.14 0.08 0.609
Serum albumin (per gr/dL) 0.46 0.09 0.83 0.015
Hypoalbuminemia (Alb < 3.5) −0.52 −0.92 −0.11 0.012 −0.459 −0.851 −0.067 0.022
Time since second vaccine dose (per day) 0.00 −0.01 0.01 0.001
ESA dose (unit per week) 0.00 0.00 0.00 0.802
Iron dose (per mg/week) 0.00 0.00 0.00 0.350

B > 0 indicates positive correlation with a log antibody titer. DM, diabetes mellitus; IHD, ischemic heart disease; BMI, body mass index; nPCR, normalized protein catabolic rate; ESA, erythropoietin stimulating agents.