Table 2.
Changes in the study parameters before and after FMT treatment in responders and nonresponders.
| Responders (n=11) | Nonresponders (n=6) | ||||||
|---|---|---|---|---|---|---|---|
| Parameter | Before FMT | After FMT (3months) | p value | Before FMT | After FMT (3months) | p value | |
| Age (years) | 55.73 ± 3.79 | 55.73 ± 3.79 | NA | 59.83 ± 3.43 | 59.83 ± 3.43 | NA | |
| Gender | NA | NA | |||||
| Male | 4 (26.7%) | 4 (26.7%) | 3 (50%) | 3 (50%) | |||
| Female | 11 (73.3%) | 11 (73.3%) | 3 (50%) | 3 (50%) | |||
| Duration of diabetes (years) | 12.36 ± 2.52 | 12.36 ± 2.52 | NA | 12.33 ± 3.37 | 12.33 ± 3.37 | NA | |
| Height (m) | 167.5 ± 2.5 | 167.5 ± 2.5 | NA | 161.2 ± 1.8 | 161.2 ± 1.8 | NA | |
| Weight (Kg) | 70.25 ± 3.59 | 69.45 ± 3.63 | 0.08 | 67.33 ± 0.84 | 68.00 ± 1.10 | 0.17 | |
| BMI (Kg/m2) | 24.99 ± 0.88 | 24.55 ± 0.92 | 0.06 | 26.31 ± 0.68 | 26.56 ± 0.79 | 0.20 | |
| Blood pressure systolic (mmHg) | 128.5 ± 3.8 | 126.4 ± 1.8 | 0.59 | 125.8 ± 4.2 | 126.2 ± 4.7 | 1.00 | |
| Blood pressure diastolic (mmHg) | 78.64 ± 3.43 | 74.09 ± 2.22 | 0.08 | 78.33 ± 1.67 | 81.17 ± 0.83 | 0.18 | |
| Fasting glucose (mmol/L) | 8.53 ± 0.37 | 6.77 ± 0.12 | <0.01 | 8.40 ± 1.32 | 8.23 ± 1.24 | 1.00 | |
| Postprandial glucose (2h, mmol/L) | 12.19 ± 0.75 | 9.28 ± 0.506 | <0.01 | 12.72 ± 1.62 | 12.55 ± 1.83 | 1.00 | |
| HbA1c (%) | 7.44 ± 0.14 | 6.77 ± 0.12 | <0.01 | 7.80 ± 0.33 | 7.97 ± 0.40 | 0.12 | |
| Alanine Transaminase, ALT (IU/L) | 25.78 ± 2.93 | 22.75 ± 2.37 | 0.08 | 22.13 ± 3.15 | 20.47 ± 3.16 | 0.31 | |
| Aspartate Aminotransferase, AST (IU/L) | 22.82 ± 3.00 | 23.74 ± 3.07 | 0.57 | 19.93 ± 3.50 | 21.87 ± 3.95 | 0.09 | |
| Uric acid, UA (µmol/L) | 310.2 ± 18.2 | 256.6 ± 15.5 | <0.01 | 307.8 ± 54.6 | 263.5 ± 37.3 | 0.09 | |
| Cholesterol: total (mmol/L) | 3.56 ± 0.34 | 3.24 ± 0.35 | 0.28 | 4.55 ± 0.38 | 4.70 ± 0.24 | 0.56 | |
| Cholesterol: triglycerides (mmol/L) | 2.21 ± 0.44 | 1.77 ± 0.380 | 0.03 | 2.31 ± 0.64 | 2.26 ± 0.57 | 0.84 | |
| Cholesterol: HDL (mmol/L) | 0.90 ± 0.06 | 0.88 ± 0.08 | 0.42 | 1.08 ± 0.14 | 0.95 ± 0.10 | 0.16 | |
| Cholesterol: LDL (mmol/L) | 2.07 ± 0.29 | 1.82 ± 0.31 | 0.21 | 2.88 ± 0.20 | 3.42 ± 0.20 | 0.03 | |
| Blood urea nitrogen (mmol/L) | 6.02 ± 0.42 | 5.92 ± 0.54 | 1.00 | 7.03 ± 0.10 | 5.82 ± 0.33 | 0.17 | |
| Serum creatinine concentration, SCr (µmol/L) | 62.87 ± 5.28 | 61.46 ± 3.56 | 0.70 | 68.15 ± 7.12 | 67.05 ± 6.84 | 0.84 | |
| Fasting C-peptide (ng/ml) | 2.39 ± 0.48 | 2.71 ± 0.40 | 0.24 | 2.16 ± 0.50 | 2.35 ± 0.50 | 0.22 | |
| Postprandial C-peptide (2h, ng/ml) | 4.69 ± 0.82 | 5.75 ± 1.04 | 0.02 | 4.16 ± 0.87 | 4.97 ± 0.86 | 0.22 | |
P values were obtained by Mann–Whitney paired test.
Continuous variables are shown as the means (SD) and categorical variables as indicated.
HbA1c of 7.44% converts to 58 mmol/mol, 6.77% to 50 mmol/mol, 7.8% to 62 mmol/mol, and 7.97% to 64 mmol/mol. NA, Not applicable.