TABLE 1.

Lymph node metastasis frequency of MDA231‐derived cells

	2 (w)	3 (w)	4 (w)	7 (w)
Parental cell	0/3 a	0/3	0/3	NM b
Meta‐1	1/4	2/4	3/4	NM
Meta‐2	0/3	0/3	1/3	NM
Control shRNA (Meta‐1)	0/5	2/5	2/5	5/5
CCR7 shRNA (Meta‐1)	0/6	0/6	0/6	5/5

Luciferase‐expressing cells were orthotopically injected into the right inguinal mammary fat pad of 6‐9‐w‐old female SCID mice on day 0, and bioluminescence signal was detected by IVIS.

^a Number of mice with detectable signals of axillary lymph node metastasis/number of mice with tumor at injection site.

^b Not measured.