TABLE 2.
Univariate and multivariate analyses of overall survival.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| Age (≥ 60 vs. < 60) | 1.25(0.87,1.81) | 0.234 | − | − |
| Gender (Female vs. Male) | 1.28(0.88,1.86) | 0.197 | − | − |
| Family history of cancer (Yes vs. No) | 1.13(0.77,1.68) | 0.532 | − | − |
| TNM stage (II vs. I) | 1.42(0.87,2.32) | 0.158 | 1.02(0.57,1.82) | 0.944 |
| TNM stage (III vs. I) | 2.68(1.75,4.08) | <0.001 | 1.76(1.07,2.88) | 0.025 |
| TNM stage (IV vs. I) | 5.5(1.7,17.82) | 0.005 | 3.84(1.17,12.57) | 0.026 |
| Histologic grade (G3–G4 vs. G1–G2) | 1.14(0.79,1.67) | 0.481 | − | − |
| Ishak score (5–6 vs. 0–4) | 0.87(0.5,1.5) | 0.613 | − | − |
| Child–Pugh grade (B–C vs. A) | 1.66(0.82,3.36) | 0.159 | − | − |
| Vascular invasion (Micro vs. None) | 0.51(0.23,1.14) | 0.101 | 0.77(0.33,1.82) | 0.556 |
| Vascular invasion (Macro vs. None) | 0.44(0.21,0.93) | 0.032 | 0.87(0.39,1.93) | 0.735 |
| Alpha fetoprotein (Positive vs. Negative) | 1.2(0.78,1.83) | 0.412 | − | − |
| Residual tumor (R1–R2 vs. R0) | 1.16(0.47,2.86) | 0.74 | − | − |
| Risk score (High vs. Low) | 5.29(3.35,8.35) | <0.001 | 4.45(2.75,7.23) | <0.001 |
The bold values indicate they are statistically significant (p < 0.05).