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. 2022 Mar 25;13:847291. doi: 10.3389/fendo.2022.847291

Figure 2.

Figure 2

Brown adipocytes exhibit unique plasticity in response to environmental cues. In response to changes in ambient temperature, BAT-resident adipocytes undergo physiologic changes. Through trans-differentiation, adipocytes alter lipid droplet morphology, expression of thermogenic genes and mitochondrial function. During cold exposure, adipocyte proportions shift towards BA-H prominence, while thermoneutrality shifts the population towards a whitened state.