TABLE 3.
Characteristics of the five patients with fluconazole maintenance therapy failure
| Characteristic | Value |
|---|---|
| Mean age (yr [range]) | 32 (22–47) |
| No. (%) of males | 4 (80) |
| Risk factor for HIV infection (no. [%] of patients) | |
| Intravenous drug use | 5 (100) |
| Male homosexual activity | 0 |
| Mean CD4 cell count (no. of cells/μl [range]) | 41.4 (139–0) |
| CDCa stage of AIDS (no. [%] of patients) | |
| B3 | 1 (20) |
| C3 | 4 (80) |
| Previous OPC (no. [%] of patients) | |
| Total | 4 (80) |
| Fluconazole therapy | 4 (80) |
| Previous CIb | |
| Total | 3 (60) |
| Fluconazole therapy | 3 (60) |
| Clinical outcome (no. [%] of patients) | |
| Death | 4 (80) |
| Survival | 1 (20) |
a
CDC, Centers for Disease Control and Prevention.
b
CI, cryptococcal infection.