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AhR activation of (a) tryptamine, (b) l-kynurenine, (c) oxindole, (d) indole, and (e) tryptophan, measured with the CALUX reporter assay, expressed as percent of the positive control (β-naphthoflavone, 5 μM) using luciferase production as the readout. Data are expressed as mean of 3 replicates ± SEM, and different letters above the bar represent statistically significant different responses compared to each concentration.
