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. 2022 Apr 8;10:goac009. doi: 10.1093/gastro/goac009

Figure 3.

Figure 3.

Schematic representation of digoxin-to-dihydrodigoxin conversion with the involvement of E. lenta. The heme binding domain of Cgr1 transfers electrons to the extra-cytoplasmic terminal electron reductase Cgr2 through heme, resulting in reduction of digoxin to dihydrodigoxin.