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. 2022 Mar 15;14(3):1406–1432.

Figure 4.

Figure 4

A summary on few of the mechanistic roles of miRNAs, lncRNAs and circRNAs on the pathogenesis of AML and CML. A. Effects of circPVT1 and lncRNA UCA1 on the miR-125 family have been shown. Their mechanistic effects on the pathogenesis of AML have been presented. B. Effects of circNPM1 75001 and circ-ANAPC7 on the miR-181 family has been shown in the pathogenesis of AML. C. Effects of the hsa_circ family on the miR-181 family and miR-16 family in the pathogenesis of CML have been shown. D. Effect of miR-21 in both AML and CML has been shown, along with special focus on the lncRNA MEG3 in CML. E. Effect of the lncRNA MALAT on miR-328 and in the pathogenesis of CML has been shown. F. The role of the PVT1 gene loci in formation of circ-PVT1 and lncPVT1 in proliferation of AML has been shown. G. Role of lncRNA UCA1 in proliferation of both AML and CML has been shown.