TABLE 1.
MICs for A. baumannii RYC 52763/97, recipient strain E. coli TG1, clone E. coli TG1 (OXA-24) harboring the plasmid pBMB-1, and the A. baumannii RYC 30222/97 clinical strain
| Antibiotic(s) | MIC (μg/ml) for:
|
|||
|---|---|---|---|---|
| A. baumannii RYC 52763/97 (OXA-24, AmpC, TEM-1) | E. coli TG1 | E. coli TG1(pBMB-1) (OXA-24) | A. baumannii RYC 30222/97 | |
| Ampicillin | >1,024 | 4 | 128 | 32 |
| Ampicillin + clavulanic acida | >1,024 | 4 | 64 | 16 |
| Ampicillin + sulbactama | >1,024 | 2 | 64 | 4 |
| Ampicillin + tazobactama | >1,024 | 2 | 32 | 16 |
| Ticarcillin | >1,024 | 4 | 256 | 8 |
| Cefazolin | >256 | 8 | 32 | >256 |
| Cefuroxime | >256 | 4 | 4 | 64 |
| Cefoxitin | >256 | 4 | 4 | 128 |
| Cefotaxime | >256 | 0.06 | 0.06 | 8 |
| Ceftazidime | >256 | 0.12 | 0.25 | 2 |
| Ceftazidime + clavulanic acid | >256 | 0.12 | 0.25 | 2 |
| Ceftazidime + sulbactam | >256 | 0.12 | 0.25 | 0.5 |
| Ceftazidime + tazobactam | >256 | 0.12 | 0.12 | 0.5 |
| Cefepime | 256 | 0.06 | 0.12 | 4 |
| Cefpirome | >256 | 0.06 | 0.12 | 8 |
| Aztreonam | >256 | 0.06 | 0.12 | 16 |
| Imipenem | 128 | 0.12 | 1 | 0.25 |
| Imipenem + clavulanic acid | 128 | 0.12 | 1 | 0.25 |
| Imipenem + sulbactam | 128 | 0.12 | 1 | 0.06 |
| Imipenem + tazobactam | 64 | 0.12 | 0.5 | 0.06 |
| Meropenem | 256 | 0.03 | 0.125 | 0.5 |
| Tobramycin | 4 | 0.12 | 0.12 | 0.5 |
| Ciprofloxacin | 128 | 0.03 | 0.03 | 0.25 |
a
Concentration of β-lactamase inhibitor was 4 μg/ml.