Table 3.
Serotypes of strains cultured in the study or detected using serotype-specific and serogroup-specific qPCRs.
| Serotype | NPS | saliva | NPS or saliva | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Culture | qPCR | Overall | Culture | qPCR | Overall | Culture | qPCR | Overall | |
| 1PCV10 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
| 3PCV13 | 2 | 2 | 2 | 0 | 5 | 5 | 2 | 7 | 7 |
| 4PCV10 | 0 | NR# | 0 | 0 | NR# | 0 | 0 | NR# | 0 |
| 5PCV10 | 0 | NR# | 0 | 0 | NR# | 0 | 0 | NR# | 0 |
| 6 (APCV13/BPCV10/C/D) | 14 (1/10/3/0) | 15 | 16 | 0 | 15 | 15 | 14 (1/10/3/0) | 22 | 23 |
| 7 (A/FPCV10) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 (A/L/N/VPCV10) | 1 (0/0/1/0) | 9 | 9 | 0 | 10 | 10 | 1 (0/0/1/0) | 17 | 17 |
| 10 (A/B) | 7 (7/0) | 6 | 7 | 0 | 2 | 2 | 7 (7/0) | 7 | 8 |
| 11 (A/D) | 7 (7/0) | 10 | 10 | 0 | 8 | 8 | 7 (7/0) | 14 | 14 |
| 12 (A/B/F) | 0 | 1 | 1 | 0 | 4 | 4 | 0 | 4 | 4 |
| 14PCV10 | 3 | 4 | 4 | 0 | 4 | 4 | 3 | 6 | 6 |
| 15 (A/BC/F) | 13 (6/7/0) | 22 | 22 | 1 (1/0/0) | 12 | 12 | 13 (6/7/0) | 24 | 24 |
| 16F | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 (A/B/CPCV10/F) | 1 (0/0/1/0) | 1 | 1 | 0 | 0 | 0 | 1 (0/0/1/0) | 1 | 1 |
| 19APCV13 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 2 | 2 |
| 19FPCV10 | 4 | 4 | 4 | 0 | 0 | 0 | 4 | 4 | 4 |
| 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | 1 | 1 | 1 | 0 | 2 | 2 | 1 | 3 | 3 |
| 22 (A/F) | 3 (0/3) | 8 | 8 | 0 | 3 | 3 | 3 (0/3) | 10 | 10 |
| 23A | 10 | 11 | 12 | 0 | 10 | 10 | 10 | 17 | 18 |
| 23B | 5 | 6 | 6 | 1 | 4 | 5 | 6 | 8 | 9 |
| 23FPCV10 | 5 | 4 | 5 | 0 | 4 | 4 | 5 | 6 | 6 |
| 24F& | 2 | – | 2 | 2 | – | 2 | 2 | – | 2 |
| 28F& | 2 | – | 2 | 0 | – | 0 | 2 | – | 2 |
| 31& | 1 | – | 1 | 1 | – | 1 | 2 | – | 2 |
| 33 (A/F) | 0 | 1 | 1 | 0 | 3 | 3 | 0 | 3 | 3 |
| 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 35A& | 1 | – | 1 | 0 | – | 0 | 1 | – | 1 |
| 35B | 1 | 2 | 2 | 0 | 6 | 6 | 1 | 7 | 7 |
| 35F& | 6 | – | 6 | 0 | – | 0 | 6 | – | 6 |
| 37& | 1 | – | 1 | 0 | – | 0 | 1 | – | 1 |
| 38 | 1 | 3 | 3 | 0 | 3 | 3 | 1 | 5 | 5 |
| NT@ | 5 | – | 5 | 1 | – | 1 | 6 | – | 6 |
| Total | 96 | 112 | 135 | 6 | 95 | 100 | 99a | 168b | 192c |
#An assay of insufficient specificity thus considered to be not reliable (NR), &serotypes not targeted by qPCR, thus detected by culture alone, @non-typeable S. pneumoniae strains, anumber of S. pneumoniae strains cultured from 97 carriers, bnumber of serotypes detected in 155 individuals identified as carriers of S. pneumoniae by molecular method (qPCR), cnumber of serotypes detected in 158 individuals identified as carriers of S. pneumoniae by any method used in the study, PCV10serotype targeted by PCV10 and PCV13, PCV13serotype targeted only by PCV13.