Table 2.
Characteristics of included studies.
| Author | Sample (T/C) | Age (year) | Tumor type | Intervention | Time | Out-comes | ||
|---|---|---|---|---|---|---|---|---|
| T | C | T | C | |||||
| Qu [37] | 33/33 | — | — | Breast cancer, stomach cancer, esophageal cancer, lung cancer, prostate cancer, ovarian cancer, cervical cancer, non-Hodgkinlymphoma | Shen fu injection°+°chemo-therapy | Chemo-therapy only | 4∼6 cycles | (2) |
| Yang et al. [23] | 50/46 | — | — | Breast cancer, non-Hodgkinlymphoma | Shen fu injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (3) |
| Chen et al. [22] | 47/45 | 31∼72 (58.25) | 34∼73 (60.35) | Breast cancer, stomach cancer, esophageal cancer, malignant lymphoma | Shen fu injection°+°chemo-therapy | Chemo-therapy only | 10∼14 d | (1); (2) |
| Shen [38] | 80/80 | 53.74°±°8.84 | 54.45°±°9.23 | Leukemia | Shen fu injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (2) |
| Wang et al. [24] | 50/46 | 24∼66 | 28∼65 | Breast cancer, cervical cancer, non-Hodgkinlymphoma | Shen mai injection°+°chemo-therapy | Chemo-therapy only | 3 cycles | (1) |
| Ma [39] | 50/50 | — | — | Nonsmall cell lung cancer, breast cancer, cervical cancer, ovarian cancer, kidney cancer, prostate cancer, non-Hodgkinlymphoma | Shen mai injection°+°chemo-therapy | Chemo-therapy only | 4∼6 cycles | (2) |
| Su [40] | 35/30 | 23∼67 | 26∼65 | Breast cancer, malignant lymphoma, stomach cancer, ovarian cancer | Shen mai injection°+°chemo-therapy | Chemo-therapy only | 4∼6 cycles | (1) |
| Sun et al. [41] | 42/41 | — | — | Acute myelogenous leukemia | Shen mai injection°+°chemo-therapy | Chemo-therapy only | 7 d | (1); (2) |
| Sun [42] | 40/40 | 37.20°±°11.58 | 34.73°±°14.80 | Acute myelogenous leukemia | Shen mai injection°+°chemo-therapy | Chemo-therapy only | 7 d | (1); (2) |
| Chen [25] | 45/41 | — | — | Lung cancer, breast cancer, ovarian cancer, stomach cancer, non-Hodgkinlymphoma | Shen mai injection°+°chemo-therapy | Chemo-therapy only | 7∼10 d | (1); (3) |
| Duan [43] | 31/31 | 48°±°1.62 | 49°±°1.08 | Malignant tumors (specific not available) | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 28 d | (1) |
| Gu et al. [44] | 40/40 | — | — | Malignant lymphoma | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 28 d | (1); (3) |
| Ning et al. [26] | 28/26 | 42∼72 | 40∼74 | Lung adenocarcinoma, squamous lung cancer, gastric adenocarcinoma, breast cancer, malignant lymphoma | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 2∼4 cycles | (3) |
| Wang et al. [45] | 60/60 | — | — | Breast cancer, gastric cancer, lymphoma, esophageal cancer, soft tissue sarcoma, mediastinal tumor, small cell lung cancer, malignant tumor of unknown primary site | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (2); (3) |
| Wang et al. [27] | 30/30 | — | — | Breast cancer | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 4 cycles | (1); (2); (3) |
| Wang [46] | 30/31 | 56°±°16 | 55°±°13 | Breast cancer, stomach cancer, ovarian cancer, non-Hodgkinlymphoma cervical cancer | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (2); (3); (4) |
| Cui et al. [47] | 22/20 | — | — | Breast cancer | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 4∼6 cycles | (1); (3) |
| Gong et al. [48] | 28/30 | — | — | Breast cancer | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 2 treatment courses | (3); (4) |
| Chen [28] | 30/30 | 42.93°±°9.67 | 45.73°±°9.28 | Acute myeloid leukemia, acute lymphoblastic leukemia, multiple myeloma | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 3 w | (1) |
| Cai et al. [49] | 40/40 | — | — | Breast cancer | Shen qi fu zheng injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (3) |
| Ding et al. [29] | 22/26 | — | — | Malignant tumors of the breast | Shen qi fu zheng injection/fu fang ku shen injection°+°chemo-therapy | Chemo-therapy only | 4∼6 cycles | (1) |
| Zhang [50] | 57/62 | — | — | Breast cancer | Sheng mai injection°+°chemo-therapy | Chemo-therapy only | 4 cycles | (1); (3); (4) |
| Wang et al. [36] | 36/33 | — | — | Breast cancer, ovarian cancer, stomach cancer, colon cancer | Sheng mai injection°+°chemo-therapy | Chemo-therapy only | 14 d | (1); (3); (4) |
| Yan et al. [51] | 112/104 | — | — | Leukemia, non-Hodgkinlymphoma | Sheng mai injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (2); (3); (4) |
| Guo et al. [52] | 43/43 | 43.8°±°6.5 | 45.5°±°6.2 | Breast cancer, non-Hodgkinlymphoma, multiple myeloma | Sheng mai injection°+°chemo-therapy | Chemo-therapy only | 2 w | (1) |
| He and Li [53] | 40/40 | 51.5°±°3.5 | 51.3°±°3.4 | Stomach cancer, breast cancer, ovarian cancer, malignant lymphoma | Xin mai long injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (3); (4) |
| Liu et al. [54] | 29/28 | 61.7°±°5.9 | 58.7°±°6.1 | Breast cancer, stomach cancer, ovarian cancer, malignant lymphoma | Xin mai long injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (3); (4) |
| Zou [55] | 31/30 | 40°±°11 | 45°±°7 | Breast cancer, malignant lymphoma, ovarian cancer, stomach cancer | Xin mai long injection°+°chemo-therapy | Chemo-therapy only | 6 treat-ment courses | (1); (3); (4) |
| Wu et al. [56] | 45/43 | 52.2°±°6.4 | 51.9°±°7.1 | Malignant tumors (specific not available) | Xin mai long injection°+°chemo-therapy | Chemo-therapy only | 3 cycles | (1); (3); (4) |
| Yang et al. [30] | 50/50 | 18∼60 | 19∼60 | Acute leukemia | Xin mai long injection°+°chemo-therapy | Chemo-therapy only | 3 treat-ment courses | (1); (3); (4) |
| Zhou et al. [57] | 30/28 | 45.6°±°6.4 | 44.8°±°5.8 | Malignant lymphoma, breast cancer, lung cancer, stomach cancer, ovarian cancer | Huang qi injection°+°chemo-therapy | Chemo-therapy only | 2 w | (1); (3); (4) |
| Yang and Dong [58] | 30/31 | 25∼72 | 20∼71 | Breast cancer, stomach cancer, ovarian cancer, non-Hodgkinlymphoma, cervical cancer | Huang qi injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (1); (3); (4) |
| Li [59] | 40/40 | 38.36°±°9.5 | 37.58°±°7.8 | Breast cancer | Huang qi injection°+°chemo-therapy | Chemo-therapy only | 6 cycles | (2); (3); (4) |
ST-T segment (ECG changes) change rate; creatine kinase isoenzyme (CK-MB); left ventricular ejection fractions (LVEF) changes; ventricular ejection fractions (LVEF) changes; left ventricular end diastolic dimension (LVEDD).