Table 1.
Baseline Demographics of Patients Receiving Renal Replacement Therapy
| Variable | n (%) or Median (IQR) |
|---|---|
| Age, y | 5.2 (0.4, 16.1) |
| Male sex | 40 (66.7) |
| Weight*, kg | 15.85 (4.45, 51.35) |
| Weight-for-age z-score* | −0.95 (−1.86, −0.02) |
| Height*, cm | 107.0 (54.0, 156.0) |
| Height-for-age z-score* | −1.23 (−2.27, −0.29) |
| BMI z-score* | −0.19 (−1.41, 0.73) |
| Surgical patients | 47 (78.3) |
| Cardiopulmonary bypass time, min | 238 (179, 318) |
| Cross clamp time, min | 118 (63, 202) |
| Circulatory arrest time, min | 0 (0, 2) |
| PRISM-3 score* | 13 (7, 20) |
| Percent fluid accumulation†, % | 10.3 (4.8, 17.1) |
| Lowest eGFR†, mL/min/1.73 m2 | 15.75 (11.58, 20.69) |
| Admission BUN, mg/dL | 17 (11, 26) |
| Pre-RRT BUN, mg/dL | 130 (86, 155) |
| Urine output‡, mL/kg/hr | 0.4 (0.1, 1.3) |
| Time from CICU admission to RRT, d | 14.4 (7.4, 36.2) |
| Indication for RRT | |
| Fluid removal | 19 (31.7) |
| Clearance | 26 (43.3) |
| Fluid removal and clearance | 15 (25.0) |
| Mode of RRT | |
| CRRT | 20 (33.3) |
| IHD | 22 (36.7) |
| PD | 18 (30.0) |
| Vasoactive inotropic score§ | 10 (3.2, 17.5) |
| Mechanical ventilation§ | 59 (98.3) |
| CMV | 52 (88.1) |
| HFOV | 7 (11.9) |
| Ventilator-free days‖ | 0 (0, 3) |
| ECMO during hospitalization | 42 (70) |
Values are presented as either count (with percentage of whole in parentheses) or median value (with interquartile range in parentheses).
BMI = body mass index; BUN = blood urea nitrogen; CICU = cardiac intensive care unit; CRRT = continuous renal replacement therapy; CMV = conventional mechanical ventilation; ECMO = extracorporeal membrane oxygenation; PRISM = Pediatric Risk of Mortality; eGFR = estimated glomerular filtration rate; HFOV = high frequency oscillatory ventilation; IHD = intermittent hemodialysis; IQR = interquartile range; PD = peritoneal dialysis; RRT = renal replacement therapy
Measured at CICU admission
Measured between CICU admission and RRT initiation
Measured in the 24 hours prior to RRT initiation
At time of RRT initiation
In 28 days following RRT initiation