Table 2.
Characteristics of patients achieving versus not achieving goal energy and goal protein
| Variable | Goal Energy | Goal Protein | ||||
|---|---|---|---|---|---|---|
| Achieved Goal Energy (n = 55, 91.7%) | Did Not Achieve Goal Energy (n = 5, 8.3%) | p-value | Achieved Goal Protein (n = 37, 61.7%) | Did Not Achieve Goal Protein (n = 23, 38.3%) | p-value | |
| Age, y | 3.2 (0.3, 14.8) | 15.8 (13.6, 20.3) | 0.062 | 1.9 (0.3, 9.6) | 15.0 (0.9, 19.7) | 0.048 |
| WAZ* | −1.17 (−1.95, −0.29) | 1.24 (0.98, 1.75) | <0.001 | −1.09 (−1.81, −0.36) | −0.69 (−2.06, 0.92) | 0.187 |
| HAZ* | −1.29 (−2.45, −0.32) | −0.63 (−0.74, 0.02) | 0.197 | −1.20 (−2.17, −0.25) | −1.29 (−2.78, 0.40) | 0.399 |
| BMI z-score* | −0.32 (−1.68, 0.58) | 1.65 (0.8, 2.7) | 0.006 | −0.45 (−1.68, 0.54) | 0.09 (−1.17, 2.25) | 0.086 |
| Fluid restricted | 6 (11) | 3 (60) | 0.021 | 2 (5) | 7 (30) | 0.021 |
| Single ventricle | 23 (42%) | 2 (40%) | 1.000 | 17 (46) | 8 (35) | 0.432 |
| Percent fluid accumulation†, % | 10.2 (4.4, 17.5) | 14.5 (5.2, 15.7) | 0.872 | 12.3 (8.0, 20.4) | 8.9 (0.7, 15.1) | 0.322 |
| Lowest eGFR† | 0.223 | 0.021 | ||||
| <13.28 | 16 (29) | 3 (60) | 7 (19) | 12 (52) | ||
| 13.28–19.41 | 19 (35) | 2 (40) | 14 (38) | 7 (30) | ||
| ≥19.41 | 20 (36) | 0 (0) | 16 (43) | 4 (17) | ||
| Elevated BUN‡ | 50 (91) | 5 (100) | 1.000 | 34 (92) | 21 (91) | 1.000 |
| Average intake PN (cc/kg/d) | 35.8 (17.9, 51.4) | 9.8 (7.7, 10.1) | 0.004 | 43.3 (26.6, 53.2) | 16.6 (10.1, 33.2) | <0.001 |
| Year of RRT | 1.000 | 0.026 | ||||
| 2011–2016 | 35 (63.6) | 3 (60) | 19 (51.4) | 19 (82.6) | ||
| 2017–2019 | 20 (36.4) | 2 (40) | 18 (48.7) | 4 (17.4) | ||
| Ventilator-free days | 0 (0, 3) | 0 (0, 3) | 0.564 | 0 (0, 5) | 0 (0, 1) | 0.606 |
| CICU LOS, d | 43 (25, 72) | 35.4 (33, 53.3) | 0.831 | 49.9 (30, 72) | 36.4 (22.6, 48.4) | 0.354 |
| Hospital LOS, d | 55.8 (32, 88.2) | 47.1 (44.2, 53.3) | 0.904 | 60 (32, 82.8) | 47.4 (33.8, 88.2) | 0.39 |
| Death | 36 (65.5) | 3 (60) | 1.00 | 25 (67.6) | 14 (60.9) | 0.781 |
All values median (IQR) or n (%). BMI = body mass index; BUN = blood urea nitrogen; eGFR = estimated glomerular filtration rate measured as mL/min/1.73 m2; HAZ = height-for-age z-score; IQR = interquartile range; LOS = length of stay; WAZ = weight-for-age z-score
*
Measured at CICU admission
†
Measured between CICU admission and RRT initiation
‡
BUN more than three times the upper limit of normal for age