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. 2022 Apr 8;22:373. doi: 10.1186/s12885-022-09467-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — circFARSA sponges miR-330. A Binding sites in circFARSA sequence for miR-330 determined via bioinformatics analysis. B Results of DLRA in T24 cells simultaneously transfected with miR-330/NC mimics and a luciferase reporter with WT or MUT circFARSA sequences. C Levels of miR-330 in BC and normal bladder specimens (n = 30 each) determined via qPCR. D Levels of miR-330 in BC T24, J82, 5637 and UM-UC-3 cancer cells compared with normal controls determined via qPCR. E, F Levels of miR-3 in T24 and J82 cells transfected with shRNA-NC or shRNA-circFARSA for 48 h detected via qPCR