Table 2.

RNA-Seq data used in the bio-informatic analyses

Accession-Nr.	Description	Lit. or submitter	Database
CNP0000771	hu-iPSC (from human dermal fibroblasts GM01450) and H9 into iPSC-iMSC and H9ES-iMSC	[63]	CNGBdb
PRJDB1099	hiPSC from normal and trisomy 21 donors (FANTOM) into neurons (motoneurons, dopaminergic neurons) (CAGE seq)	[64]	NCBI BioProject
PRJNA244622	H9 (WA-09, WiCell) into prefrontal cortex neurons	[73]	NCBI BioProject
PRJNA404971	H9 into neurons	[74]	NCBI BioProject
PRJNA414247	H9 (WA09) into trophectoderm cells	[75]	NCBI BioProject
PRJNA433877	H9 into rostrocaudal neurons	[76]	NCBI BioProject
PRJNA484413	H9 into endothelial cells	[77]	NCBI BioProject
PRJNA544617	H9 to EC (two protocols)	[78]	NCBI BioProject
PRJNA596331	hiPSC into neurons	Lieber Institute	NCBI BioProject
PRJNA645819	hiPSC (CD34-iPSC) into cardiomyocytes	[60]	NCBI BioProject
PRJNA674506	hiPSC (ATCC, BJFF, STAN) into chondrocytes	[62]	NCBI BioProject

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