Table 3.

Association between patient diagnosis groups and self-reported disease in the family

Patient diagnosis group		Self-reported disease in family		Unadjusted	Adjusted for age	Adjusted for sex and age
		Significantly higher frequency of disease in the family
IPF		any ILD		1.9 (1.2–3.1)	2.6 (1.5–4.3)	2.6 (1.6–4.4)
Sarcoidosis		sarcoidosis		4.3 (2.6–7.1)	3.3 (1.9–5.8)	3.3 (1.9–5.8)
IPF		pulmonary fibrosis		8.1 (4.5–14.5)	7.9 (4.1–15.1)	9.2 (4.7–17.9)
uPF		pulmonary fibrosis		4.5 (2.4–8.4)	3.9 (1.9–7.9)	4.1 (2.0–8.2)
HP		COPD		2.1 (1.2–3.8)	2.4 (1.3–4.2)	2.3 (1.3–4.2)
IPF		lung cancer		1.8 (1.2–2.8)	2.2 (1.4–3.4)	2.3 (1.4–3.5)
		Significantly lower frequency of disease in the family
Non-IPF IIP		any ILD		0.1 (0.0–0.7)	0.1 (0.0–0.8)	0.1 (0.0–0.8)
Sarcoidosis		pulmonary fibrosis		0.1 (0.1–0.2)	0.1 (0.0–0.2)	0.1 (0.0–0.2)
Sarcoidosis		non-ILD lung disease		0.7 (0.6–0.9)	0.6 (0.5–0.8)	0.6 (0.5–0.8)
Sarcoidosis		lung disease, n.s		0.6 (0.5–0.9)	0.6 (0.4–0.9)	0.6 (0.4–0.9)

For significant results (p < 0.05 Chi squared or Fisher’s exact when appropriate) the odds ratio and 95% confidence interval from logistic regression analysis (with and without adjustment for sex or age) are presented. HP = hypersensitivity pneumonitis; IPF = idiopathic pulmonary fibrosis; uPF = unclassifiable pulmonary fibrosis; non-IPF IIP = idiopathic interstitial pneumonia other than IPF; aidILD = autoimmune disease interstitial lung disease; oILD = other interstitial lung disease; n.s. = not specified