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. 2022 Apr 8;46(1):96. doi: 10.1186/s42269-022-00787-z

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — SARS-CoV-2 variants of concern (VOC). The amino acid changes have been shown in all the VOC which have been compared with the genome sequence of the spike (S) protein of the original SARS-CoV-2 strain from Wuhan, China. NTD N-terminal domain, RBD receptor binding domain, FP fusion peptide domain, HR1 Heptad repeat 1, HR2 Heptad repeat 2, TM transmembrane domain, CTD C terminal domain