Fig. 6.

A The distribution of MPSNs@R837 (red fluorescence) in tumor sections (scale bar = 200 μm). B The fluorescence intensity as described in A determined by flow cytometry. C Thermographic images and (D) tumor temperature changes of 4T1 tumor-bearing mice at different time points under laser irradiation 12 h after injection of saline, MPSNs and MPSNs@R837 (808 nm, 0.6 W/cm²). E The ROS level in (green fluorescence) in tumor sections (scale bar = 100 μm). F The fluorescence intensity as described in e. All data are mean ± SD (n = 5), statistical significances were calculated via Student’s t test, ****p < 0.0001