Fig. 8.

MPSNs@R837-mediated photo-immunotherapy in vivo: A Schematic of treatment schedule in 4T1 orthotopic mammary tumor model. Mice were randomly divided into 4 groups: (1) saline, (2) Anti-PD-L1, (3) MPSNs@R837 (+), (4) MPSNs@R837 (+) plus Anti-PD-L1. B Tumor volume (C) Tumor weight. D Number of pulmonary metastatic nodules. E Ratio of CD8 + /CD4 + T cells and (F) CTL infiltration in primary. G Survival time. H Lung tissues with metastatic nodules from 4T1 tumor-bearing mice in each group over 21 days. I Representative metastatic lung images of each group in Fig. 8. H. J Tumor images. Data are mean ± SD (n = 5), statistical significances were calculated via Student’s t test, *p < 0.05, **p < 0.01