Table 1.

Laboratory parameters after hypertonic bicarbonate aerosol and cigarette smoke exposure compared to sodium chloride treatment

Parameter	NaCl	NaHCO3	NaCl + CSE	NaHCO3 + CSE
Arterial pH	7.17	7.35 ± 0.22	7.23	7.16 ± 0.07
standard HCO3 (mmol/l)	17.1	26.9 ± 5.85	19.1	18.1 ± 1.52
PaCO2 (mmHg)	64.3	59.5 ± 10.45	59	72.83 ± 4.61
Glucose (mmol/l)	6.08 ± 0.31	6.87 ± 0.26	7.21 ± 0.54	7.35 ± 0.29
Triglyceride (mmol/l)	1.32 ± 0.21	1.27 ± 0.29	1.38 ± 0.08	1.40 ± 0.44
Total bilirubin (mmol/l)	1.10 ± 0.11	1.00 ± 0.32	0.78 ± 0.05	0.83 ± 0.19
Direct bilirubin (mmol/l)	0.33 ± 0.05	0.40 ± 0.17	0.23 ± 0.05	0.25 ± 0.06
ALT (IU/l)	71.68 ± 5.89	77.35 ± 4.63	66.60 ± 7.58	65.23 ± 6.71
AST (IU/l)	103.33 ± 21.08	85.25 ± 6.52	127.55 ± 16.81	118.55 ± 22.00
GGT (IU/I)	8.85 ± 2.28	6.48 ± 0.59	7.55 ± 0.61	7.70 ± 0.33
ALP (IU/l)	73.25 ± 4.11	71.75 ± 7.44	68.50 ± 7.40	68.50 ± 7.40
LDH (IU/l)	140.75 ± 21.55	128.25 ± 38.94	169.25 ± 21.78	142.50 ± 13.58
Cholesterol (mmol/l)	0.78 ± 0.17	0.82 ± 0.09	0.80 ± 0.05	0.93 ± 0.13
Amylase (IU/l)	2304.5 ± 126.70	2114.50 ± 132.35	2270.25 ± 128.72	2497.75 ± 136.27
Lipase (IU/I)	31.50 ± 14.65	18.50 ± 5.20	15.50 ± 0.65	25.25 ± 8.50
Total Protein (g/l)	55.23 ± 0.54	51.90 ± 0.99	52.55 ± 2.41	56.78 ± 1.98
Urea (mmol/l)	10.73 ± 0.46	10.18 ± 0.89	10.00 ± 1.25	11.28 ± 0.99
K+ (mmol/l)	9.19 ± 1.15	8.38 ± 1.37	8.47 ± 0.37	7.48 ± 0.77
Cl− (mmol/l)	94.00 ± 0.41	92.25 ± 1.93	96.00 ± 0.58	94.25 ± 0.85
Ca2+ (mmol/l)	2.89 ± 0.05	2.66 ± 0.07	2.77 ± 0.06	3.00 ± 0.04
Mg2+ (mmol/l)	1.26 ± 0.07	0.98 ± 0.06	1.09 ± 0.04	1.14 ± 0.06
P (mmol/l)	2.39 ± 0.43	1.97 ± 0.28	2.12 ± 0.08	2.19 ± 0.18
Fe (mmol/l)	36.40 ± 2.91	38.10 ± 2.78	41.10 ± 3.82	46.28 ± 5.95

Data represent mean ± SEM of 4 animals/group. PaCO₂: ALT: alanine transaminase, AST: aspartate transaminase, GGT: gamma-glutamyl-transpeptidase, ALP: alkaline phosphatase, LDH: lactate dehydrogenase, K + : potassium, Cl-: chloride, Ca2 + : calcium, Mg2 + : magnesium, P: phosphorus, Fe: iron