Table 2.
DEGs significantly enriched in neuroactive ligand-receptor interactions pathway
| tissues | DEGs | |||||
|---|---|---|---|---|---|---|
| hypothalamus | KNG1↑ | GPR83↓ | PTGDR↓ | PTGER4↑ | PTRFR↓ | LPAR3↑ |
| VIPR1↑ | CCKAR↓ | GABRA6↓ | CHRNA5↑ | CHRNA2↓ | ||
| pituitary | CHRM2↑ | ADRA2B↑ | HPH↑ | HTR2A↑ | HTR1F↑ | HTR1D↑ |
| HTR1B↑ | HTR1E↓ | AGTR↑ | GRP↑ | EDN2↑ | MC5R↑ | |
| MTNR1B↑ | S1PR1↑ | INSL5↑ | CALCB↑ | CRH↑ | CRHR2↑ | |
| GIP↑ | GLP1R↑ | GRM5↑ | GRM7↑ | GABBR2↑ | GABRA6↑ | |
| GABRG2↑ | CHRNA7↑ | GRIK1↑ | VIPR2↑ | |||
| ovary stroma | DRD1↑ | DRD3↓ | CHRM4↓ | CCKBR↓ | GALR1↓ | GALR2↓ |
| POMC↑ | TAC1↑ | TAC4↑ | AVPR1A↓ | CGA↑ | RXFP↓ | |
| GABRA5↑ | GABRG3↑ | CHRNA4↓ | GRIK3↑ | P2RX1↓ | ||
| F5 follicle membrane | GABRG3↑ | SSTR1↑ | OPRN1↓ | |||