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. 2022 Mar 21;13:836842. doi: 10.3389/fneur.2022.836842

Table 2.

Incidence rate, crude, and adjusted hazard ratios for major depressive disorder among study patients.

Major depressive disorder occurrence over 1-year follow-up Total
(n = 750,544)
Patients with tinnitus
(n = 375,272)
Comparison group
(n = 375,272)
No. % No. % No. %
Yes 5,812 0.77 4,382 1.17 1,430 0.38
Incidence per 100 person-years (95%CI) 0.78 (0.76~0.80) 1.17 (1.14~1.21) 0.38 (0.36~0.40)
Crude HR (95% CI) - 3.07*** (2.89~3.26) 1.00
Adjusteda HR (95% CI) - 3.08*** (2.90~3.27) 1.00
***

Indicates p < 0.001. HR, hazard ratio.

a

Adjustment for patient's sex, age, urbanization level, monthly income, geographic region, hypertension, hyperlipidemia, coronary heart disease, and diabetes.