TABLE 3.

P values of pair-wise comparison of fungal burden data for isolate 1 (nikkomycin MIC, ≥64 μg/ml)

Agents compared (mg/kg/dose)	Antigen		Quantitative culture
	Lung	Spleen	Lung	Spleen
Amphotericin B (2.0) to itraconazole (75)	NSa	0.0124	NS	NS
Amphotericin B (2.0) to nikkomycin Z (100)	NS	0.0244	<0.0001	<0.0001
Amphotericin B (2.0) to nikkomycin Z (20)	<0.0001	0.0014	<0.0001	<0.0001
Itraconazole (75) to nikkomycin Z (100)	<0.0001	<0.0001	<0.0001	<0.0001
Itraconazole (75) to nikkomycin Z (20)	<0.0001	<0.0001	<0.0001	<0.0001
Nikkomycin Z (100) to nikkomycin Z (20)	0.0373	NS	0.0052	<0.0001

^aNS, not significant; P > 0.05