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. 2022 Mar 12;75(1):e572–e578. doi: 10.1093/cid/ciac212

Table 2.

Geometric Mean Concentration of Anti-SARS-CoV-2 Spike IgG Antibodies Among Healthcare Workers in the 11 months Following Vaccination Against COVID-19, Israel, December 2020 to October 2021

Total Number 
in Category T1 T 2 T3 T4 T5 T6
Group n GMC CI n GMC CI n GMC CI n GMC CI n GMC CI N GMC CI
Previously infected, received boosterb 18 35 876.6 566.4–1356.7 28 583.9 411–829.4 25 471 331.2–670 21 268.4 185.6–388.2 4 121.5 41.8–353.1 7a 2016.3 1010.1–4024.7
Previously infected, not boostedb 100 2 120..9 22.6–646.4
Infected between tests 4 and 5 (not boosted) 22 12 64.1 43.8–93.6 14 246..6 176.1–345.5 11 305.1 189.1–492.3 11 184.4 115.4–294.5 17 2704.3 1353.5–5403.3 11 3699.9 2759.6–4960.6
Infected between tests 5 and 6 (not boosted) 17 10 44.8 25.6–78.4 11 205.2 170.2–247.4 15 209.4 161.4–271.5 12 128.2 86.4–190.3 10 165.1 65.9–414 8 6805.3 3791.1–12215.7
Never infected, fully 
vaccinated (3 doses)b 740 500 63.9 60.3–67.9 529 197.3 189.9–205.1 526 223.4 211.1–236.5 506 139.1 130.4–148.4 419 114.9 106.6–123.9 302a 2618.4 2411.4–2843
Never infected, 2 doses 
(no booster)b 116 5 150.9 25.6–890.4
<35, never infected, fully vaccinated (3 doses) 167 112 79.7 70.3–90.2 110 243.1 219–269.9 96 288.3 253.8–327.5 96 177.8 158.3–199.6 76 132.8 117.1–150.6 46a 3208.2 2689–3827.7
35–44 never infected, fully vaccinated (3 doses) 186 130 66.7 60–74.3 133 202.4 185.8–220.5 127 216.3 195.5–239.3 118 131.8 115.9–149.7 107 113.7 101.9–126.9 76a 2079.3 1768.2–2445.3
45–54 never infected, fully vaccinated (3 doses) 185 119 63.5 56.7–71 135 196.3 185.1–208.1 147 225.3 202.4–250.7 130 146.3 129.2–165.5 129 118 103.3–136.6 84a 2605.7 2252.2–3014.7
≥55+ never infected, fully vaccinated (3 doses) 204 130 51.8 45.5–59.1 142 165.3 156.5–174.7 146 192.1 170.6–216.2 153 118.7 103.7–135.8 96 98.7 79.4–122.7 91a 2806.2 2370.4–3322.4
35–54 never infected, Jewish fully vaccinated (3 doses) 228 189 64.9 59–71.3 205 197.6 187.5–208.2 216 217.4 199.3–237.1 194 144.9 131.1–160.2 199 122.3 108.9–137.4 122a 2409.2 2146.6–2703.9
35–54 never infected, Arab (incl Druze) fully ­vaccinated (3 doses) 234 179 68.2 61–76.2 214 201.3 188.6–214.9 218 234.5 214.7–256.2 194 149.9 134.3–167.2 195 134.3 118.6–152.1 117a 2640.3 2313–3013.8

Abbreviations: CI, confidence interval; COVID-19, coronavirus disease 2019; GMC, geometric mean concentration; IgG, immunoglobulin G; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Indicates groups and timepoints where IgG levels were measured post boosting.

Where groups are similar except for boosting, timepoints prior to the booster are reported together.