Table 2.

Multivariable Logistic Regression Analysis for Risk Factors of Rheumatic Symptoms Following Coronavirus Disease 2019 at 12-Month Follow-up

Variable	Odds Ratio (95% CI)
Age (per 10-year age increase)	1.22 (1.06–1.40)
Sex
Men	Ref
Women	1.58 (1.12–2.23)
Hypertension	.90 (.60–1.34)
Diabetes	.93 (.54–1.58)
Cardiovascular diseases	1.42 (.83–2.42)
Highest 7-category scale during hospitalization
3: Admitted to hospital, not requiring supplemental oxygen	Ref
4: Admitted to hospital, requiring supplemental oxygen	1.01 (.67–1.51)
5–6: Admitted to hospital, requiring HFNC, MV, ECMO, or combination	1.55 (.77–3.12)
Treatment during hospitalization
Corticosteroids	1.05 (.66–1.68)
Antivirals	.95 (.67–1.35)
Thymosin	.81 (.49–1.32)
IVIG	1.19 (.75–1.89)
Length of hospital stay, d	1.01 (1.00–1.03)
ICU admission	1.15 (.50–2.65)

For association of sex, corticosteroids, antivirals, thymosin, IVIG, length of hospital stay, and admission of ICU with rheumatic symptoms, these variables were included in the models together with age, disease severity, and comorbidity including hypertension, diabetes, and cardiovascular disease. For association of disease severity and rheumatic symptoms, the aforementioned variables were all adjusted for in the model, except for length of hospital stay and admission of ICU. Disease severity was not included in the model when exploring the association of comorbidity with rheumatic symptoms. In the model for association of age and rheumatic symptoms, only age and sex were adjusted.

Abbreviations: CI, confidence interval; ECMO, extracorporeal membrane oxygenation; HFNC, high-flow nasal cannula for oxygen therapy; ICU, intensive care unit; IVIG, intravenous immunoglobulin; MV, mechanical ventilation.