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. Author manuscript; available in PMC: 2022 Apr 8.
Published in final edited form as: Adv Exp Med Biol. 2021;1344:57–69. doi: 10.1007/978-3-030-81147-1_4

Fig. 4.1.

Fig. 4.1

Overview of dopamine-related activity in the reward system. Dopamine levels peak in the active phase when tyrosine hydroxylase (TH) levels are high while monoamine oxidase A (MAOA) levels are low and dopamine transporter (DAT) activity is decreased. This corresponds to core clock gene expression in the striatum, which regulates the expression of these dopamine metabolism-related gene expressions