Table 5.
Viral aetiologies and rates of pneumococcal colonisation according to age and severity/mortality (n = 570)
| Total N (%) | Age category (%) | Case category (%) | ||||||
|---|---|---|---|---|---|---|---|---|
| 1–11 months old | 1–5 years old | 6–12 years old | Non-severe cases | Severe cases | Fatal cases | |||
| Total N (%) | 570 | 381 (67) | 178 (31) | 11 (2) | 463 (81) | 107 (19) | 28 (5) | |
| Detected number(s) of virus(es) | No virus | 68 (12) | 48 (13) | 18 (10) | 2 (18) | 57 (12) | 11 (10) | 3 (11) |
| 1 virus | 291 (51) | 196 (51) | 88 (49) | 7 (64) | 233 (50) | 58 (54) | 20 (71) | |
| 2 viruses | 163 (29) | 106 (28) | 56 (31) | 1 (9) | 131 (28) | 32 (30) | 2 (7) | |
| 3 viruses | 43 (8) | 27 (7) | 15 (8) | 1 (9) | 38 (8) | 5 (5) | 3 (11) | |
| 4–5 viruses | 5 (1) | 4 (1) | 1 (1) | 0 (0) | 4 (1) | 1 (1) | 0 (0) | |
| Detected virus* | RSV (Any) | 252 (44) | 198 (52) | 54 (30) | 0 (0) | 206 (44) | 46 (43) | 7 (25) |
| RSV A | 59 (10) | 48 (13) | 11 (6) | 0 (0) | 46 (10) | 13 (12) | 3 (11) | |
| RSV B | 203 (36) | 158 (41) | 45 (25) | 0 (0) | 167 (36) | 36 (34) | 6 (21) | |
| Influenza virus (Any) | 53 (9) | 26 (7) | 24 (13) | 3 (27) | 41 (9) | 12 (11) | 8 (29) | |
| Influenza virus A | 51 (9) | 25 (7) | 23 (13) | 3 (27) | 39 (8) | 12 (11) | 8 (29) | |
| Influenza virus B | 2 (0) | 1 (0) | 1 (1) | 0 (0) | 2 (0) | 0 (0) | 0 (0) | |
| hMPV | 75 (13) | 40 (10) | 34 (19) | 1 (9) | 64 (14) | 11 (10) | 3 (11) | |
| Enterovirus | 69 (12) | 36 (9) | 32 (18) | 1 (9) | 57 (12) | 12 (11) | 4 (14) | |
| hRV | 161 (28) | 123 (32) | 35 (20) | 3 (27) | 126 (27) | 35 (33) | 4 (14) | |
| PIV (Any) | 32 (6) | 18 (5) | 14 (8) | 0 (0) | 29 (6) | 3 (3) | 1 (4) | |
| PIV1 | 13 (2) | 8 (2) | 5 (3) | 0 (0) | 11 (2) | 2 (2) | 1 (4) | |
| PIV2 | 11 (2) | 5 (1) | 6 (3) | 0 (0) | 11 (2) | 0 (0) | 0 (0) | |
| PIV3 | 11 (2) | 7 (2) | 4 (2) | 0 (0) | 10 (2) | 1 (1) | 1 (4) | |
| hCoV NL63 | 3 (1) | 1 (0) | 2 (1) | 0 (0) | 3 (1) | 0 (0) | 0 (0) | |
| hCoV OC43 | 1 (0) | 1 (0) | 0 (0) | 0 (0) | 1 (0) | 0 (0) | 0 (0) | |
| hCoV 229E | 3 (1) | 2 (1) | 0 (0) | 1 (9) | 2 (0) | 1 (1) | 0 (0) | |
| hCoV HKU | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
| Adenovirus | 76 (13) | 34 (9) | 39 (22) | 3 (27) | 65 (14) | 11 (10) | 2 (7) | |
| hBoV | 29 (5) | 17 (4) | 12 (7) | 0 (0) | 21 (5) | 8 (7) | 1 (4) | |
| Pneumococcal colonization | 259 (45) | 170 (45) | 83 (47) | 6 (55) | 217 (47) | 42 (39) | 9 (32) | |
*If two or more viruses were detected in one patient, each detected virus was counted and listed in the table
All categorical data are presented as number (percentage, %)
Total N total number, RSV respiratory syncytial virus, hMPV human metapneumovirus, hRV human rhinovirus, PIV parainfluenza virus, hCoV human coronaviruses, hBoV human bocavirus, PCR polymerase chain reaction