Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 2;4(4):946–964. doi: 10.20517/cdr.2021.82

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021.

© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Factors causing resistance to anti-cancer drugs in ABCB1- or ABCG2-overexpressing colon cancer cell lines and an ABCB1-overexpressing HeLa cell line. Resistance factors for SN-38, irinotecan, topotecan, mitoxantrone, anthracyclines, 5-fluorouracil, and platinum anticancer drugs are shown relative to the respective parental cell lines. Cell lines are HCT116-SN6 [2004 (COL), ABCG2-overexpressing colon cancer cell^[10] (orange)], S1-IR20 [2021 (COL), ABCG2-overexpressing colon cancer cell^[11] (gray)], S1-B1-20 [2000 (COL), ABCB1-overexpressing colon cancer cell^[12] (yellow)], and Hvr100-6 [2002 (HeLa), ABCB1-overexpressing HeLa cell^[13] (blue)]. Establishments of these resistant sublines are described in Table 1. ND: Not determined.