Table 2.
Circulating miRNAs and lncRNAs in advanced ovarian cancer
| miRNAs | Source | Regulation | Association with | Ref. |
|---|---|---|---|---|
| miR-7 | Serum | Up | Metastasis | [134] |
| miR-30a-5p | Urine | Up | Lymph node metastasis | [135] |
| miR-30a-5p | Urine exosomes | Up | Migration | [135] |
| miR-92 | Serum | Up | Lymph node metastases | [136] |
| miR-99a-5p | Serum exosomes | Up | Invasion | [137] |
| miR-101 | Serum exosomes | Down | Migration | [138] |
| miR-125b | Serum | Up | Metastasis | [139] |
| miR-130a | Serum | Up | Recurrence | [140] |
| miR-145 | Serum | Down | Migration | [141] |
| miR-145 | Serum | Down | Metastasis | [142] |
| miR-148a | Plasma | Down | Lymph node metastases | [143] |
| miR-183 | Serum | Up | Lymph node metastases | [144] |
| miR-193a-5p | Serum | Down | Lymph node metastases | [145] |
| miR-193a-5p | Plasma | Down | Recurrence | [146] |
| miR-199a | Serum | Down | Metastasis | [147] |
| miR200a, miR200b, miR200c, miR141, miR429, miR203a, miR34b, miR34a | Plasma | Up | EMT | [148] |
| miR-200b, miR-200c | Serum exosomes | Up | Lymph node metastasis | [149] |
| miR-200b, miR-200c | Serum | Up | Lymph node metastasis | [150] |
| miR-375 | Serum exosomes | Up | Lymph node metastases | [151] |
| miR-376a | Serum | Up | Metastasis | [152] |
| miR-423-5p | Plasma | Down | Invasion | [153] |
| miR-429 | Serum | Up | Migration, invasion | [134] |
| miR-590-3p | Plasma | Up | Metastasis | [154] |
| miR-940 | Ascites exosomes | Up | Migration | [155] |
| miR-1273g-3p | Serum | Down | Recurrence | [156] |
| lncRNAs | ||||
| MALAT1 | Serum exosomes | Up | Metastasis | [157] |
| LINK-A | Plasma | Up | Metastasis | [158] |
| LINK-A | Serum | Up | Metastasis | [159] |
miRNAs: microRNAs; lncRNAs: long-non coding RNAs; EMT: epithelial-mesenchymal transition; MALAT1: metastasis-associated lung adenocarcinoma transcript 1