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. 2019 Sep 19;2(3):618–633. doi: 10.20517/cdr.2019.55

Table 3.

DMEs of Phase II and miRNAs that regulate their expression

Target miRNA Model Drug Reference
UGT1A1 miR-21-3p NS NS Papageorgiou et al.[53], 2017
miR-141-3p
miR-200a-3p
UGT2B4 miR-216b-5p HepG2 Epirubicin Dluzen et al.[51], 2016
miR-135a NS NS Wijayakumara et al.[54], 2017
miR-410
UGT2B7 miR-3664
UGT2B10 miR216b-5p Liver cancer Epirubicin Dluzen et al.[51], 2016
UGT2B17 miR-376c NS NS Margaillan et al.[52], 2016
GSTP1 miR-133a Head and neck, oesophageal, bladder Cisplatin and carboplatin Moriya et al.[50], 2012
SULT1A1 miR-631 Breast cancer Actinomycin D Yu et al.[47], 2010

NS: not stated; DMEs: drug metabolizing enzymes