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. 2019 Sep 19;2(3):471–489. doi: 10.20517/cdr.2019.22

Figure 2.

Figure 2

Open-and-close movement of the two halves of P-gp (A) The Definition of DCOM is given as the distance (the dotted line) between the center of mass of NBD1 and that of NBD2. (B) Different DCOM gap distances among some of the structures of P-gp in the inward-open conformation